منابع مشابه
HPV vaccines and cervical cancer.
Human papillomavirus (HPV) vaccines have opened a new perspective on the prevention of cervical cancer, one of the most paradigmatic long-term goals of the cancer prevention field. For decades, prevention has been and still is partially fulfilled by the expansion of the practice of cervical cytology (the Pap smear) repeated frequently in tens of millions of asymptomatic women worldwide. The pra...
متن کاملChapter 17: Second generation HPV vaccines to prevent cervical cancer.
Prophylactic human papillomavirus (HPV) vaccines based on intramuscular injection of non-infectious L1 virus-like particles (VLPs) are undergoing intense clinical evaluation. As documented in preceding chapters of this monograph, clinical trials of these vaccines have demonstrated their safety and high efficacy at preventing type-specific persistent cervical HPV infection and the development of...
متن کاملHuman papillomavirus (HPV) vaccines: prospects for eradicating cervical cancer.
Journal of Family Planning and Reproductive Health Care 2004: 30(4) Introduction One of the most important developments of the past 25 years in cancer biology has been the evidence that infection with human papillomaviruses (HPVs) in the lower genital tract is the cause of virtually all cases of cervical carcinoma in women and a smaller, less defined fraction of vulvar, vaginal, anal and penile...
متن کاملVaccines for cervical cancer.
The review focuses on current and future prevention of invasive cervical cancer (ICC), the second most common cancer among women worldwide. Implementation of population-based cytological screening programmes, using the 'Pap' smear to detect pre-cancerous lesions in the cervix, has resulted in substantial declines in mortality and morbidity from ICC in North America and some European countries. ...
متن کاملChapter 21: Modelling the impact of HPV vaccines on cervical cancer and screening programmes.
The impact of human papillomavirus (HPV)-16/18 vaccination on the incidence of infection and disease can be explored in a range of different models. Here we explore the epidemiological and economic impact of vaccination where screening is absent and where it is well established. The importance for epidemiology of assumptions about naturally-acquired immunity and heterogeneity in risk behaviours...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2008
ISSN: 0923-7534
DOI: 10.1093/annonc/mdn310